Anti-Cystatin C (3C8) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CST3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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3C8-2E9-8C5
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 ELISA: 1/10000
Immunogen
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Purified recombinant protein expressed in E.coli.
Molecular Weight
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Calculated MW: 16 kDa; Observed MW: 16 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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1471
Uniprot ID
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P01034
Background
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Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors. Most cell types secrete Cystatin C. Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion. In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-β1 signaling.
Research Area
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Tags & Cell Markers
Synonyms
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CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin