Anti-CTNNB1(S45P Mutant) Mouse Monoclonal Antibody

Anti-CTNNB1(S45P Mutant) Mouse Monoclonal Antibody
Anti-CTNNB1(S45P Mutant) Mouse Monoclonal Antibody

Anti-CTNNB1(S45P Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for Beta catenin, CTNNB, Catenin beta-1 detection, Test with IHC-P, ICC/IF, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • IHC-P
  • ICC
  • IF
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07296
$680.00

Shipping To:
United States

Product Information

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Target
    Beta catenin, CTNNB, Catenin beta-1
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    2M6-M2-D8
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • IHC-P
  • ICC
  • IF
  • ELISA
Application Details
    ELISA: 1/1000-1/2000,ICC/IF: 1/50-1/100,IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of CTNNB1 which includes the mutation of S45P, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    CTNNB1 protein is a dual function protein. It is a subunit of a complex of proteins that from adherent Anti-CTNNB1(S45P) Mouse Monoclonal Antibody junctions, which are important for the establishment and maintenance of epithelial cell layers by regulating cell growth and adhesion between adjacent cells. CTNNB1 protein also pulls double duty as an intracellular signal transducer in the Wnt signaling pathway. Mutations of CTNNB1 have been implicated in the pathogenesis of several cancers.
Research Area
    Cell Biology
Synonyms
    Beta catenin, CTNNB, Catenin beta-1
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Product Image

Western blot analysis of recombinant CTNNB1 (D32N) and wild type proteins. Purified His-tagged CTNNB1 (D32N) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-CTNNB1(D32N) monoclonal.