Anti-CTLA4 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CTLA4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN249
Isotype
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IgG1
Reactivity
Application
Application Details
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IHC: 1/200
Immunogen
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Full length human recombinant protein of human CTLA4 (NP_001032720) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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1493
Uniprot ID
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P16410
Background
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Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Research Area
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Immunology
Synonyms
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CD152,Cytotoxic T-lymphocyte protein 4,CD152,Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4)