Anti-Cox-17 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
COX17
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/200 IF: 1/50-1/200
Immunogen
-
Synthetic peptide corresponding to the N-terminal of Human Cox-17.
Molecular Weight
-
Calculated MW: 7kDa
Formulation
-
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
-
Liquid
Gene ID
-
10063
Uniprot ID
-
Q14061
Background
-
Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.
Research Area
-
-
Synonyms
-
Cytochrome c oxidase copper chaperone; COX17