Anti-Cortactin Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CTTN
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-2C5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthetic peptide of human Cortactin
Molecular Weight
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Calculated MW: 62 kDa; Observed MW: 80-85 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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2017
Uniprot ID
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Q14247
Background
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Cortactin a cytoskeletal protein that that is involved in coordinating actin reorganization during cell movement. Localizes at the leading edge of lamellipodia during cell migration. Its amino-terminal acidic domain associates with the Arp2/3 and WASP complex at F-actin branches.
Research Area
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Signal Transduction
Synonyms
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CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1