Anti-CoREST Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
RCOR1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R01-3N9
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
-
A synthesized peptide derived from human CoREST
Molecular Weight
-
Calculated MW: 53 kDa; Observed MW: 66 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
23186
Uniprot ID
-
Q9UKL0
Background
-
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
COREST; Nr2b2; RCOR; Rcor1; Rxrb