Anti-COPS3 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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COPS3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-8E6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human COPS3
Molecular Weight
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Calculated MW: 48 kDa; Observed MW: 48 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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8533
Uniprot ID
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Q9UNS2
Background
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Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.
Research Area
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Neuroscience
Synonyms
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COPS3; CSN3; COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; JAB1-containing signalosome subunit 3