Anti-Clusterin Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CLU
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R93-8K-4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human Clusterin
Molecular Weight
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Calculated MW: 52 kDa;Observed MW:40kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1191
Uniprot ID
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Q06890
Background
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Isoform 1:Functions as extracellular chaperone that prevents aggregation of non native proteins (PubMed:11123922, PubMed:19535339).Prevents stress-induced aggregation of blood plasma proteins (PubMed:11123922, PubMed:12176985, PubMed:17260971, PubMed:19996109).Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro) (PubMed:12047389, PubMed:17412999, PubMed:17407782).
Research Area
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Immunology
Synonyms
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AAG4; Aging-associated gene 4 protein; APOJ; ApoJalpha; ApoJbeta; Apolipoprotein J; CLI; CLU; Clusterin alpha chain; Clusterin; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor; Complement cytolysis inhibitor b chain; complement lysis inhibitor; Ku70-binding protein 1; KUB1; NA1/NA2; SGP2; sulfated glycoprotein 2; Testosterone-repressed prostate message 2; TRPM2;