Anti-Cleaved N-terminal GSDMD Rabbit Monoclonal Antibody

Algentbio Antibody
Algentbio Antibody

Anti-Cleaved N-terminal GSDMD Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for GSDMD detection, Test with WB in Human

Reactivity
  • Human
Application
  • WB
Host
  • Rabbit
Catalog Number
    ABXB65002
$370.00

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United States

Product Information

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Target
    GSDMD
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R07-2C4
Isotype
    IgG
Reactivity
  • Human
Application
  • WB
Application Details
    WB: 1/500-1/1000
Immunogen
    A synthetic peptide of human Cleaved N-terminal GSDMD
Molecular Weight
    Calculated MW: 53 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    79792
Uniprot ID
    P57764
Background
    Gasdermin-D, N-terminal
    Promotes pyroptosis in response to microbial infection and danger signals (PubMed:26375003, PubMed:26375259, PubMed:27418190, PubMed:28392147, PubMed:32820063, PubMed:34289345).
    Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1, CASP4 or CASP5 in response to canonical, as well as non-canonical (such as cytosolic LPS) inflammasome activators (PubMed:26375003, PubMed:26375259, PubMed:27418190).
Research Area
    Cell Biology
Synonyms
    Gasdermin-D; DFNA5L; FKSG10; GSDMDC1;Gasdermin domain-containing protein 1
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