Anti-Cleaved C-terminal GSDMD Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GSDMD
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-7E6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Cleaved C-terminal GSDMD
Molecular Weight
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Calculated MW: 53 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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79792
Uniprot ID
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P57764
Background
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The full-length protein before cleavage is inactive: intramolecular interactions between N- and C-terminal domains mediate autoinhibition in the absence of activation signal (PubMed:26375003, PubMed:28928145, PubMed:29576317, PubMed:32109412).
Research Area
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Cell Biology
Synonyms
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Gasdermin-D; DFNA5L; FKSG10; GSDMDC1;Gasdermin domain-containing protein 1