Anti-Claudin 18.2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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Claudin18.2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-1O2
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Claudin 18.2.
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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51208
Uniprot ID
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P56856-2
Background
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Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity).
Required for lung alveolarization and maintenance of the paracellular alveolar epithelial barrier (By similarity).
Acts as a negative regulator of RANKL-induced osteoclast differentiation, potentially via relocation of TJP2/ZO-2 away from the nucleus, subsequently involved in bone resorption in response to calcium deficiency (By similarity).
Research Area
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Signal Transduction
Synonyms
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A2;CLDN18.2