Anti-CHTOP Rat mAb

Algentbio Antibody
Algentbio Antibody

Anti-CHTOP Rat mAb

Rat IgG2a Monoclonal for Chtop detection, Test with WB, IHC-F, IHC-P, ICC/IF, IP in Mouse

Reactivity
  • Mouse
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
Host
  • Rat
Catalog Number
    ABXB06820
$400.00

Shipping To:
United States

Product Information

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Target
    Chtop
Host
  • Rat
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    7C4
Isotype
    IgG2a
Reactivity
  • Mouse
Application
  • WB
  • IHC-F
  • IHC-P
  • ICC
  • IF
  • IP
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
    The C-terminal fragment of mouse CHTOP
Molecular Weight
    Calculated MW: 26 kDa; Observed MW: 26 kDa
Formulation
    Liquid in PBS containing 0.09% sodium azide as a preservative.
Form
    Liquid
Gene ID
    66511
Uniprot ID
    Q9CY57
Background
    Plays an important role in the ligand-dependent activation of estrogen receptor target genes (By similarity). May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.Required for the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC methylates H4R3 and transactivates genes involved in glioblastomagenesis.
Research Area
    -
Synonyms
    CHTOP; Friend of PRMT1 protein; Small arginine- and glycine-rich protein; SRAG
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Primary Antibodies of Algent Bio were identified for Q&C tests by multiimmunology applications which were performed with different cell or tissue samples.