Anti-CDT1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CDT1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Immunogen
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Recombinant protein of human CDT1
Molecular Weight
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Calculated MW: 60 kDa; Observed MW: 65 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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81620
Uniprot ID
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Q9H211
Background
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Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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CDT 1; Chromatin licensing and DNA replication factor 1; Retroviral integration site 2; RIS2