Anti-CDK11A/CDK11B Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CDK11A/CDK11B
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human CDK11A/CDK11B
Molecular Weight
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Calculated MW: 92 kDa; Observed MW: 92 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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728642/984
Uniprot ID
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Q9UQ88/P21127
Background
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Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Research Area
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Cell Biology
Synonyms
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CDC2L2; CDC2L3; p58GTA; PITSLRE; CDK11-p46; CDK11-p58; CDK11-p110 / p58; PK58; CDK11; CLK-1; CDC2L1; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110