Anti-CDK1/CDC2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CDK1
Host
Storage
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Store at -20°C. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-7B-5
Isotype
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IgG
Reactivity
Application
Immunogen
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Peptide
Molecular Weight
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–
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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983
Uniprot ID
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P06493
Background
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Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis.
Research Area
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Cell Biology
Synonyms
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CDC2, CDC28A, CDKN1, P34CDC2