Anti-CDC42 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CDC42
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-4B8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/30 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human CDC42
Molecular Weight
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Calculated MW: 21 kDa; Observed MW: 21 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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998
Uniprot ID
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P60953
Background
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Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.
Research Area
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Cell Biology
Synonyms
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CDC42; CDC42Hs; G25K; TKS