Anti-CDC27 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CDC27
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-6S-1
Isotype
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IgG
Reactivity
Application
Application Details
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WB：1/500-1/1000，IHC-P：1/50-1/100，ICC/IF：1/50，FC：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 92 kDa; Observed MW:92 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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996
Uniprot ID
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P30260
Background
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Cell division cycle protein 27 homolog (CDC27) is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Research Area
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Cell Biology
Synonyms
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APC3, ANAPC3