Anti-CD81 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CD81
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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8M2-M8-Z3
Isotype
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IgG1
Reactivity
Application
Application Details
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ICC/IF：1/50：FC，1/50-1/100
Immunogen
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Peptide
Molecular Weight
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–
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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975
Uniprot ID
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P60033
Background
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CD81 belongs to the tetraspanin family, which is characterized by four transmembrane domains, one short extracellular domain (ECL1), and one long extracellular domain (ECL2). Tetraspanins interact with a variety of cell surface proteins and intracellular signaling molecules in specialized tetraspanin enriched microdomains (TEMs) where they mediate a range of processes including adhesion, motility, membrane organization, and signal transduction. CD81, like other tetraspanins, is enriched in exosomes. Many research studies demonstrate a role for CD81 in lymphocyte signaling. CD81 is also a well-characterized receptor for Hepatitis C Virus and facilitates the entry of the virus into target cells.
Research Area
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Cell Biology
Synonyms
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TAPA1, Tetraspanin-28