Anti-CD49c Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ITGA3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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5N7-N7-Q5
Isotype
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IgG1/Kappa
Reactivity
Application
Application Details
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FC：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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–
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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3675
Uniprot ID
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P26006
Background
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CD49c is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. CD49c provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. It may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Research Area
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Tumor biology
Synonyms
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ITGA3, MSK18