Anti-CD46 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CD46
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-1H-5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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Peptide
Molecular Weight
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Calculated MW:44 kDa;Observed MW: 50-70 kDa
Formulation
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Liquid in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Form
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Liquid
Gene ID
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4179
Uniprot ID
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P15529
Background
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CD46 is a type I membrane protein and a regulatory part of the complement system. This protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, CD46 can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria.
Research Area
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Immunology
Synonyms
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MCP; MIC10; TLX; TRA2.10; CD46