Anti-CD146 Mouse Monoclonal Antibody

Anti-CD146 Mouse Monoclonal Antibody
Anti-CD146 Mouse Monoclonal Antibody
Anti-CD146 Mouse Monoclonal Antibody
Anti-CD146 Mouse Monoclonal Antibody

Anti-CD146 Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for MCAM detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00355
$400.00

Shipping To:
United States

Product Information

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Target
    MCAM
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    ZN154
Isotype
    IgG1
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/50-1/100
Immunogen
    Full length human recombinant protein of human MCAM (NP_006491) produced in HEK293T cell.
Molecular Weight
    -
Formulation
    PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
    Liquid
Gene ID
    4162
Uniprot ID
    P43121
Background
    CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development.
Research Area
    Immunology
Synonyms
    CD146; MUC18;Cell surface glycoprotein MUC18;Melanoma-associated antigen MUC18
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Product Image

Immunohistochemistry analysis of paraffin-embedded human melanoma using CD146 antibbody. High-pressure and temperature Accel 3in1 EDTA pH 8.7 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded Human endometrium tissue using CD146 antibbody. High-pressure and temperature Tris-EDTA pH 9.0 was used for antigen retrieval.