Anti-CD133 (6H10) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PROM1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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6H10-F1-C11
Isotype
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IgG2a
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant human Prominin-1 protein fragments expressed in E.coli.
Molecular Weight
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Calculated MW: 97 kDa; Observed MW: 133 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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8842
Uniprot ID
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O43490
Background
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This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area
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Neuroscience
Synonyms
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Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.