Anti-CCR4 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CCR4
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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7D9-H3-W8
Isotype
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IgG2b/Kappa
Reactivity
Application
Application Details
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FC：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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–
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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1233
Uniprot ID
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P51679
Background
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High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Research Area
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Cell Biology
Synonyms
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CMKBR4, CD194