Anti-CBP Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CREBBP
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-8Z-6
Isotype
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IgG/kappa
Reactivity
Application
Application Details
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WB：1/500-1/1000，ICC/IF：1/50
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 300 kDa; Observed MW:300 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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1387
Uniprot ID
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Q92793
Background
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CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene.The CREB protein carries out its function by activating transcription, where interaction with transcription factors is managed by one or more CREB domains: the nuclear receptor interaction domain (RID), the KIX domain (CREB and MYB interaction domain), the cysteine/histidine regions (TAZ1/CH1 and TAZ2/CH3) and the interferon response binding domain. The CREB protein domains, KIX, TAZ1 and TAZ2, each bind tightly to a sequence spanning both transactivation domains 9aaTADs of transcription factor p53.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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CREBBP, CREB-binding protein