Anti-CB1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CNR1
Host
Storage
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Store at -20°C to -80°C for 12 months in lyophilized form.
Clonality
Clone Number
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R07-9Q-6
Isotype
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IgG
Reactivity
Application
Application Details
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FC: 1/50-1/100 ELISA: 1/10000
Immunogen
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Recombinant human CB1 protein
Molecular Weight
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-
Formulation
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Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Form
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Lyophilized
Gene ID
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1268
Uniprot ID
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P21554
Background
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This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Research Area
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Neuroscience
Synonyms
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CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6