Anti-Caspase 7 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CASP7
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human CASP7
Molecular Weight
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Calculated MW: 34 kDa; Observed MW: 34 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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840
Uniprot ID
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P55210
Background
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Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death.
Research Area
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Cell Biology
Synonyms
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MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3