Anti-Caspase 14 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CASP14
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Fusion protein of human CASP14
Molecular Weight
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Calculated MW: 28 kDa; Observed MW: 28 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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23581
Uniprot ID
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P31944
Background
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Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. May also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes.
Research Area
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Cell Biology
Synonyms
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CASP14; Caspase-14; Caspase 14; MICE; CASP-14