Anti-Cardiac Troponin C Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TNNC1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R01-3Y3
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Cardiac Troponin C
Molecular Weight
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Calculated MW: 18 kDa; Observed MW: 18 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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7134
Uniprot ID
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P63316
Background
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Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
Research Area
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Cell Biology
Synonyms
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tnnc1a; TNC; Tnnc1; TNNI3; Troponin C