Anti-Caldesmon/CDM Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CALD1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-8L-5
Isotype
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IgG
Reactivity
Application
Application Details
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IHC-P：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 93 kDa; Observed MW:75 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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800
Uniprot ID
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Q05682
Background
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Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping.
Research Area
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Tumor biology
Synonyms
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CALD, CAD, CALD1