Anti-Cadherin-7 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CDH7
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/200
Immunogen
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Synthetic peptide corresponding to Human Cadherin-7.
Molecular Weight
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Calculated MW: 87kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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1005
Uniprot ID
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Q9ULB5
Background
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The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-7 is a member of the atypical type II cadherin family that lacks the HAV cell recognition sequence found in type I cadherins. Although the absence of an HAV sequence decreases cell adhesion specificity, cadherin-7 contributes to cell organization by mediating homophilic cell adhesion in the brain, testis and prostate.
Research Area
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Synonyms
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Cadherin-7; CDH7; CDH7L1