Anti-CABLES1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CABLES1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human CABLES1
Molecular Weight
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Calculated MW: 68 kDa; Observed MW: 68 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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91768
Uniprot ID
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Q8TDN4
Background
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This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.
Research Area
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Cell Biology
Synonyms
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CABL1; IK3-1; CABLES; HsT2563