Anti-C3 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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C3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-2D7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human C3
Molecular Weight
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Calculated MW: 187 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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718
Uniprot ID
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P01024
Background
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Plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Research Area
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Immunology
Synonyms
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AHUS5; ARMD9; ASP; Complement C3; Complement factor 3; CPAMD1; HEL S 62p