Anti-c-Jun (10G2) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
JUN
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
10G2-2G3-1F4
Isotype
-
IgG1
Reactivity
Application
Application Details
-
IHC: 1/50-1/100
Immunogen
-
Synthetic peptide conjugated to KLH.
Molecular Weight
-
-
Formulation
-
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
-
Liquid
Gene ID
-
3725
Uniprot ID
-
P05412
Background
-
c-jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39