Anti-BUBR1 Mouse Monoclonal Antibody

Anti-BUBR1 Mouse Monoclonal Antibody
Anti-BUBR1 Mouse Monoclonal Antibody
Anti-BUBR1 Mouse Monoclonal Antibody
Anti-BUBR1 Mouse Monoclonal Antibody

Anti-BUBR1 Mouse Monoclonal Antibody

Mouse IgG1 Monoclonal for BUB1B detection, Test with IHC-P in Human

Reactivity
  • Human
Application
  • IHC-P
Host
  • Mouse
Catalog Number
    ABXB00316
$400.00

Shipping To:
United States

Product Information

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Target
    BUB1B
Host
  • Mouse
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    ZN7
Isotype
    IgG1
Reactivity
  • Human
Application
  • IHC-P
Application Details
    IHC: 1/50-1/100
Immunogen
    Protein expressed in 293T cell transfected with human BUB1B expression vector
Molecular Weight
    -
Formulation
    PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
    Liquid
Gene ID
    701
Uniprot ID
    O60566
Background
    This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Research Area
    Cell Biology
Synonyms
    BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
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Product Image

Immunohistochemistry analysis of paraffin-embedded lung cancer tissue using BUBR1 antibbody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded human endometrial carcinoma using BUBR1 antibbody. High-pressure and temperature ACCEL pH 8.7 was used for antigen retrieval.