Anti-BUB3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
BUB3
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Fusion protein of human BUB3
Molecular Weight
-
Calculated MW: 37 kDa; Observed MW: 37 kDa
Formulation
-
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
-
Liquid
Gene ID
-
9184
Uniprot ID
-
O43684
Background
-
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis.
Research Area
-
Cell Biology
Synonyms
-
BUB3; Mitotic checkpoint protein BUB3