Anti-BUB1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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BUB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-1E2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Bub1
Molecular Weight
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Calculated MW: 122 kDa; Observed MW: 122 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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699
Uniprot ID
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O43683
Background
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Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1.
Research Area
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Cell Biology
Synonyms
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Bub1; BUB1A; BUB1L; hBUB1