Anti-BRCC45 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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BABAM2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human BRE
Molecular Weight
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Calculated MW: 44 kDa; Observed MW: 44 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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9577
Uniprot ID
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Q9NXR7
Background
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Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs).
Research Area
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Cell Biology
Synonyms
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BRCC4; BRCC45; BRE