Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody

Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody
Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody
Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody
Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody

Anti-BRCA1(C61G Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP detection, Test with WB, IHC-P, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07287
$680.00

Shipping To:
United States

Product Information

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Target
    BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    6N9-Y3-D8
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Application Details
    ELISA: 1/1000-1/2000,WB: 1/500-1/1000,IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of BRCA1 which includes the mutation of C61G, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    BRCA1 is normally expressed in cells of breast and other tissues, where it helps repair damaged DNA or destroy cells if DNA cannot be repaired. It is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double-strand breaks. If BRCA1 itself is damaged by a BRCA1 mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP
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Product Image

Western blot analysis of recombinant BRCA1(C61G) and wild type proteins.Purified His-tagged BRCA1(C61G) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-BRCA1(C61G) monoclonal.
Immunofluorescence of cells expressing BRCA1 proteins with Anti-BRCA1(C61G).HEK293T cells were transfected with pCDNA3-GFP-BRCA1 (WT) plasmid (left column) or pCDNA3-GFP-BRCA1(C61G) plasmid (right column), then fixed and stained with Anti-BRCA1(C61G) monoclonal.