Anti-beta Catenin Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CTNNB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-1E2
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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A synthetic peptide of human beta Catenin
Molecular Weight
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Calculated MW: 85 kDa; Observed MW: 85 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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1499
Uniprot ID
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P35222
Background
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Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
Research Area
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Signal Transduction
Synonyms
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CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin