Anti-Bcl2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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BCL2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-7T-7
Isotype
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IgG
Reactivity
Application
Application Details
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WB：1/500-1/1000，IHC-P：1/50-1/100
Immunogen
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Peptide
Molecular Weight
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Calculated MW: 26 kDa; Observed MW:26 kDa
Formulation
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Liquid in PBS, Glycerol and BSA
Form
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Liquid
Gene ID
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596
Uniprot ID
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P10415
Background
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Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
Research Area
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Cell Biology
Synonyms
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BCL2, Apoptosis regulator Bcl-2