Anti-Bcl2 Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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BCL2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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ZN225
Isotype
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IgG2a
Reactivity
Application
Application Details
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IHC: 1/50-1/100
Immunogen
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Full length human recombinant protein of human BCL2 (NP_000624) produced in HEK293T cell.
Molecular Weight
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-
Formulation
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PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Form
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Liquid
Gene ID
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596
Uniprot ID
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P10415
Background
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This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]
Research Area
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Cell Biology
Synonyms
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BCL2; Apoptosis regulator Bcl-2