Anti-BAG1 (2C12) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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BAG1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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2C12-A8-1D7
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant human Bag1 protein fragments expressed in E.coli.
Molecular Weight
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Calculated MW: 39 kDa; Observed MW: 52,46,33 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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573
Uniprot ID
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Q99933
Background
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Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.Inhibits the pro-apoptotic function of PPP1R15A,and has anti-apoptotic activity.Markedly increases the anti-cell death function of BCL2 induced by various stimuli.
Research Area
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Cell Biology
Synonyms
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BAG1; HAP; BAG family molecular chaperone regulator 1; BAG-1; Bcl-2-associated athanogene 1