Anti-BACE2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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BACE2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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Recombinant fusion protein
Molecular Weight
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Calculated MW:56kDa
Formulation
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Liquid in PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Form
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Liquid
Gene ID
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25825
Uniprot ID
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Q9Y5Z0
Background
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This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Research Area
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Synonyms
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ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; BACE2