Anti-Aurora A (2E3) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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AURKA
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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2E3-C10-C11-G6
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200
Immunogen
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Purified recombinant human Aurora Kinase A protein fragments expressed in E.coli.
Molecular Weight
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Calculated MW: 46 kDa; Observed MW: 46 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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6790
Uniprot ID
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O14965
Background
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Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis.
Research Area
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Cell Biology
Synonyms
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AIK; ARK1; AYK1; Aurora-A; Aurora-related kinase 1; BTAK; IAK1; Ipl1- and aurora-related kinase 1; STK15; STK6; Serine/threonine kinase 15