Anti-ATPBD3 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CTU1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human ATPBD3.
Molecular Weight
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Calculated MW: 36kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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90353
Uniprot ID
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Q7Z7A3
Background
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Cytoplasmic tRNA 2-thiolation protein 1, plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Research Area
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-
Synonyms
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Cytoplasmic tRNA 2-thiolation protein 1; ATphospho-binding domain-containing protein 3; Cancer-associated gene protein; Cytoplasmic tRNA adenylyltransferase 1; CTU1; ATPBD3; NCS6