Anti-ATP1A4 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
ATP1A4
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
Recombinant fusion protein
Molecular Weight
-
Calculated MW:114kDa
Formulation
-
Liquid in PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Form
-
Liquid
Gene ID
-
480
Uniprot ID
-
Q13733
Background
-
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 4 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
Research Area
-
-
Synonyms
-
ATP1A1; ATP1AL2; ATP1A4