Anti-ATG7 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ATG7
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R09-4E8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human Apg7
Molecular Weight
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Calculated MW: 78 kDa; Observed MW: 78 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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10533
Uniprot ID
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O95352
Background
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The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
Research Area
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Cell Biology
Synonyms
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hAGP7; Ubiquitin-activating enzyme E1-like protein; APG7L