Anti-ATG16L1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
ATG16L1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R05-8U2
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human Atg16L1
Molecular Weight
-
Calculated MW: 68 kDa; Observed MW: 68 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
55054
Uniprot ID
-
Q676U5
Background
-
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Research Area
-
Cell Biology
Synonyms
-
ATG16L1; APG16L; Autophagy-related protein 16-1; APG16-like 1