Anti-ATG16L1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ATG16L1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-4G8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant protein of human ATG16L1
Molecular Weight
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Calculated MW: 68 kDa; Observed MW: 68 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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55054
Uniprot ID
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Q676U5
Background
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Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Research Area
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Cell Biology
Synonyms
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ATG16L1; APG16L; Autophagy-related protein 16-1; APG16-like 1