Anti-ATAD2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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ATAD2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-5M5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human ATAD2
Molecular Weight
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Calculated MW: 159 kDa; Observed MW: 180 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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29028
Uniprot ID
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Q6PL18
Background
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May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Research Area
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Cell Biology
Synonyms
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ANCCA; Atad2; CT137; L16; PRO2000